1,633 research outputs found

    Gravitational Biology Facility on Space Station: Meeting the needs of space biology

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    The Gravitational Biology Facility (GBF) is a set of generic laboratory equipment needed to conduct research on Space Station Freedom (SSF), focusing on Space Biology Program science (Cell and Developmental Biology and Plant Biology). The GBF will be functional from the earliest utilization flights through the permanent manned phase. Gravitational biology research will also make use of other Life Sciences equipment on the space station as well as existing equipment developed for the space shuttle. The facility equipment will be developed based on requirements derived from experiments proposed by the scientific community to address critical questions in the Space Biology Program. This requires that the facility have the ability to house a wide variety of species, various methods of observation, and numerous methods of sample collection, preservation, and storage. The selection of the equipment will be done by the members of a scientific working group (5 members representing cell biology, 6 developmental biology, and 6 plant biology) who also provide requirements to design engineers to ensure that the equipment will meet scientific needs. All equipment will undergo extensive ground based experimental validation studies by various investigators addressing a variety of experimental questions. Equipment will be designed to be adaptable to other space platforms. The theme of the Gravitational Biology Facility effort is to provide optimal and reliable equipment to answer the critical questions in Space Biology as to the effects of gravity on living systems

    Why the old traditions will not fail: landscape, legends, and the construction of place at Dartmouth College

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    Dartmouth College, located in Hanover, New Hampshire, is one of the nine Colonial Colleges and a member of the exclusive Ivy League. Congregationalist minister Eleazar Wheelock founded Dartmouth in 1769 on the premise of training missionaries to Christianize the Indians of the region and, over the years, Dartmouth developed into a premier college. Dartmouth is famous for its traditions, its ardently loyal alumni, and as a classic New England liberal arts college. But this image does not correspond with a closer, more critical look at the College. Through both archival and ethnographic research, this dissertation examines the cultural landscape, folklore, place-making, and student culture of Dartmouth College. Recurring themes include the persistence and preservation of Dartmouth’s many “old traditions” and a vague but frequently used term, “the Dartmouth Experience.” Primary research questions ask: What are the “old traditions” and why is Dartmouth adamant about not letting them fail? Why are these traditions important to understanding Dartmouth as a culture and place? And what is “the Dartmouth Experience?” Chapter 1 provides an introduction and outlines the dissertation’s content. Chapter 2 discusses the methodology, the main concepts employed, and a literature review. Chapter 3 provides some general historical background on the College and a description of contemporary Dartmouth. Chapter 4 is a landscape history of Dartmouth Hall and its role as an iconic building of the College. Chapter 5 explores the folklore surrounding the Old Pine, a site for the controversial and now-defunct Class Day ritual. Chapter 6 examines the Dartmouth Outing Club and Dartmouth Night, two key traditions that define Dartmouth as a place. Chapter 7 takes the reader inside the “Dartmouth Bubble” to gain a sense of daily life at the Ivy League school. Chapter 8 recounts my experiences as an outsider at Dartmouth and integrates the preceding chapters’ findings to understanding its place identity. Chapter 9 examines the role of the Ivy League in the American mind, the persistence of tradition at Dartmouth, and “the Dartmouth Experience.” Chapter 10 concludes with an argument on why the old traditions will not fail

    Hyperglycemia may alter cytokine production and phagocytosis by means other than hyperosmotic stress

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    In the previous issue of Critical Care, Otto and colleagues used in vitro studies to explore the theory that immunomodulation, by correction of hyperglycemia, may be a contributing factor to the reported efficacy of intensive insulin therapy (IIT) in critically ill patients. They suggested that hyperglycemia via hyperosmolarity at supra-physiological levels potentiates the production of cytokines by peripheral blood mononuclear cells in response to lipopolysaccharide (LPS) stimulation and that it also reduces the responses of phagocytosis and oxidative burst in human granulocytes. The efficacy of IIT, they concluded, may be partially due to the correction of hyperosmolality. Other studies, however, have suggested that immunological responses to LPS in the presence of hyperglycemia are mediated by a mechanism other than hyperosmolality

    A History of the Arkansas State Music Teachers\u27 Association

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    This study records a documented history of the Arkansas State Music Teachers Association from its inception in 1915 to the present. It also presents significant areas in which the Association has contributed to music throughout the state. Major sources of data were letters of communication, convention programs, the Arkansas Music Teacher publication, memorandums in mimeographed form and personal interviews with past . officers of the Association. This study has been organized into a chronological sequence of events which took place in the development of the Association, the program of annual conventions, significant contributions of the Association and a general summary of the work. This study has revealed that the Association has aided in advancing the cause of music in Arkansas through certification and accreditation, through student contests and festivals, through student chapters and through the promotion of the concept that music should be provided for every child in every school in Arkansas
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